Stephen Cusack | PhD
Stephen Cusack has been group leader and head of the EMBL Grenoble outstation since 1989. Stephen Cusack received his PhD in 1976 from the Imperial College, London, UK. Postdoctoral work led him to EMBL Grenoble, France, where he worked as staff scientist 1980–1989. The Cusack group is engaged in structural biology research of RNA-protein complexes in gene expression and host-pathogen interactions. Stephen Cusack has an outstanding track record in structural biology. Current research included the field of influenza virus research, leading to elucidation of crucial viral functional domains and the crystallographic structural analysis using the powerful X-ray beams of the European Synchrotron Radiation Facility (ESRF). The most recent results, forming the basis for Savira’s foundation, led to the corresponding patents and two key publications in Nature Structural and Molecular Biology.
Hugo Kubinyi | PhD
Hugo Kubinyi studied chemistry in Vienna, Austria. After his Ph.D. thesis at the Max Planck Institute of Biochemistry in Munich he continued as a PostDoc at the German Cancer Research Centre in Heidelberg. In 1966 he joined Knoll AG, Development of a partial synthetic cardiac glycoside (Meproscillarin, CLIFT; launched 1978). In 1985 he moved to BASF AG. Since 1987, until his retirement in summer 2001, he was responsible for the Molecular Modelling, X-ray Crystallography and Drug Design group of BASF, since early 1998 also for Combinatorial Chemistry in the Life Sciences. In 1986 he was appointed as associate Professor of Pharmaceutical Chemistry at the University of Heidelberg. In 2006 he received the Herman Skolnik Award (CINF, ACS) and in 2008 the Nauta Award in Pharmacochemistry (EFMC) and the Nauta Chair (Vrije Universiteit, Amsterdam). From his scientific work resulted more than 100 publications and seven books on QSAR, 3D QSAR, Drug Design, Chemogenomics in Drug Discovery, and Drug Discovery Technologies.
Klaus Klumpp | PhD
Klaus Klumpp has been leading research and development activities at Roche in the area of viral diseases since 1997, most recently as Vice President and Global Head of Virology Discovery. Research performed under his direction at Roche sites in Welwyn Garden City (UK), Palo Alto (USA) and Nutley (USA) has supported clinical development of antiviral drugs such as Tamiflu for the treatment and prophylaxis of influenza virus infection, and Balapiravir, Mericitabine and Danoprevir, new antiviral agents for the treatment of HCV infection. He has led Roche Research Teams and also worked extensively in R&D collaborations with external partner companies and academic laboratories, resulting in the discovery and transition into clinical development of a number of new leads and drug candidates for the treatment of acute and chronic viral diseases including influenza, Hepatitis C, Hepatitis B, Dengue and HIV. Examples for a few of these new leads and candidates have been published, including inhibitors of novel influenza virus targets, HIV RNase H and inhibitors of HIV reverse transcriptase and HCV polymerase. Klaus also held research fellow positions at GlaxoWellcome Research and Development (Stevenage, UK) and the European Molecular Biology Laboratory (EMBL) institutes (Heidelberg, Germany and Grenoble, France). Klaus is a Founder of Riboscience LLC and a scientific consultant to Novira Therapeutics Inc..
Udo Elsner | PhD
Udo Elsner is lawyer in Vienna since almost 20 years, an expert in corporate and contract law with a special focus in pharmaceutical companies and life science biotechnology and pharma business. He is providing consulting services in connection with negotiation of R&D collaboration agreements, technology transfer from universities to companies, and license agreements.